The Impact of Fortetropin Supplementation on Dogs Recovering from TPLO Surgery
The impact of the nutrition product, Fortetropin on muscle atrophy in dogs recovering from TPLO surgery was evaluated in a randomized, double-blinded, placebo-controlled study involving 100 dogs. Fortetropin is an advanced nutrition product that is manufactured using a proprietary process that involves non-thermal pasteurization and freeze drying. Dogs in the Fortetropin and placebo (cheese powder) groups were evaluated at baseline and during the 8 and 12 week post-operative periods. Following surgery, dogs experienced 8 weeks of forced exercise restriction, gradually resuming physical activity during weeks 9 - 12. Evaluation parameters included: thigh circumference measurements, stance force analysis, serum myostatin and C-reactive protein concentration measurements, ultrasonographic assessments of thigh and epaxial muscle thickness, and muscle condition scoring. During the period of forced exercise restriction from week 0 - 8, when comparing Fortetropin® supplementation to placebo: 1) Fortetropin® prevented a rise in serum myostatin levels, 2) Fortetropin® minimized the loss of muscle mass as measured by thigh circumference in the affected and unaffected limbs and 3) Fortertropin® supplemented dogs had a more significant improvement in percent of weight supported by the affected limb as determined by force plate stance analysis (more rapid return to normal stance force distribution).